Evidence-Based Medicine

Herpangina

Herpangina

Description

  • Highly contagious viral infection primarily affecting infants and children, characterized by painful oral lesions
  • Oral lesions are usually limited to mucosa of posterior oropharynx
    • often involves anterior tonsillar pillars and soft palate
    • other common locations include uvula and tonsils
    • rare locations include posterior buccal surfaces and dorsal tip of tongue

Diagnosis

  • Diagnosis usually made clinically based on characteristic oral lesions and accompanying fever in children ≤ 5 years old1
  • Diagnosis may be confirmed by serum antibodies and/or virus culture from intact vesicles, but clinical diagnosis usually sufficient1

Management

  • Treatment usually symptomatic due to mild, self-limiting nature of infection
    • palliative mouth rinses and gargles may reduce pain from oral lesions
    • avoid steroid-containing preparations
  • No evidence for benefit with any currently available antiviral therapy

Published: 24-06-2023 Updeted: 24-06-2023

References

  1. Lynch DP. Oral viral infections. Clin Dermatol. 2000 Sep-Oct;18(5):619-28
  2. Scott LA, Stone MS. Viral exanthems. Dermatol Online J. 2003 Aug;9(3):4
  3. Romero JR. Pediatric group B coxsackievirus infections. Curr Top Microbiol Immunol. 2008;323:223-39